A GENE REGULATORY NETWORK COOPERATIVELY CONTROLLED BY PDX1 AND SOX9 GOVERNS LINEAGE ALLOCATION OF FOREGUT PROGENITOR CELLS

A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells

The generation of pancreas, liver, and intestine from a common pool of progenitors in the foregut endoderm requires the establishment of organ boundaries.How dorsal foregut progenitors activate pancreatic genes and evade the intestinal lineage choice remains unclear.Here, we identify Pdx1 and Sox9 as cooperative inducers of a gene regulatory networ

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Evaluation of microRNA expression in head and neck squamous cell carcinoma cell lines and in primary culture of oral keratinocytes

ABSTRACT Objective: Functional in vitro studies are fundamental to understand the role of microRNAs, small non coding RNA molecules that function as post-transcriptional regulators, in cancer.The objective of this study was to determine the applicability of head and neck squamous cell carcinoma cell lines and human oral keratinocytes as models for

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DIALEKTIKA DEMOKRASI DALAM BINGKAI POLITIK PRIMORDIALISME PILKADA

Momentum pemilihan kepala daerah sulit dilepaskan dari politik primordialisme dalam bentuk kebudayaan lokal suatu daerah.Faktor 1004 etnisitas, kesukuan, agama hingga praktik dan ritual budaya memiliki pengaruh besar terhadap substansi penyelenggaraan pilkada.Artikel ini menuliskan praktik politik primordialisme sebagai bagian dari demokrasi lokal

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